Ulcerative Colitis: Promising Therapies for Remission and Disease Management

2 minute read

By Paul Howorth

Ulcerative colitis (UC) is a chronic inflammatory bowel disease that affects the large intestine. While there is no cure, treatments exist that can induce and maintain remission.

Clinical Remission With Fecal Microbiota Transplantation

Fecal microbiota transplantation (FMT) is a procedure in which fecal material from a healthy donor is transferred to the colon of a person with UC. This procedure has shown great promise in inducing clinical remission in UC patients.1

Vedolizumab’s efficacy in moderate-to-severe UC

Vedolizumab is an integrin receptor antagonist that has been approved for the treatment of moderate-to-severe UC. A 2021 study published in the journal Gut found that vedolizumab induced clinical remission in 47.7% of patients at week 52, compared to 25.5% of patients receiving placebo.2 This demonstrates vedolizumab’s effectiveness in controlling disease activity and inducing remission in patients with moderate-to-severe UC.

Early, intensive biologics for remission and prevention

Early and intensive treatment with biologics, such as infliximab or vedolizumab, has been shown to be effective in inducing and maintaining remission in patients with UC. Early intervention with biologics can prevent disease progression and complications. By suppressing inflammation and controlling disease activity, biologics can help patients achieve long-term remission and improve their overall quality of life.

Start a Search Today!

If you or someone you know is living with ulcerative colitis, it’s important to explore all available treatment options. By searching online, you can learn more about these promising therapies and connect with healthcare professionals who can provide personalized guidance and support. Take control of your health and start your journey toward remission today.

Paul Howorth

Contributor